Disease: Hashimoto Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VIP P01282 vasoactive intestinal peptide Signaling 4.2E-04 0.437 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
TNFSF13B Q9Y275 TNF superfamily member 13b 0.98 0.460 0.731
TNFRSF25 Q93038 TNF receptor superfamily member 25 8.6E-03 0.573 0.769
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TG P01266 thyroglobulin Enzyme modulator 2.9E-59 0.480 0.808
TBX21 Q9UL17 T-box transcription factor 21 Transcription factor 1.00 0.541 0.808
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
S100A9 P06702 S100 calcium binding protein A9 Calcium-binding protein 0.48 0.433 0.885
S100A8 P05109 S100 calcium binding protein A8 Calcium-binding protein 0.14 0.430 0.962
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PSC Cholangitis, primary sclerosing 0.603 0.731
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923